Swollen feet should first be registered with nephrology. Foot edema firstly consider edema caused by nephritis and nephropathy, the patient should go to the nephrology clinic to check the urine routine, the urine routine suggests positive urine protein, at this time we should further improve the examination. It is necessary to check the 24-hour urine protein quantification, kidney function, kidney ultrasound, and actively exclude the relevant tests that cause secondary nephropathy, such as urine this week protein, serum protein electrophoresis, immune complete set, rheumatic complete set, lupus complete set, tumor markers, infection eight. Patients with indications for renal biopsy are recommended to have renal biopsy to clarify the type of pathology, guide the treatment and determine the prognosis.