Acute appendicitis during pregnancy is a relatively common surgical disease during pregnancy, with a general incidence of 0.1% in pregnant women. Acute appendicitis can occur in all stages of pregnancy, and the high incidence in mid-term pregnancy may be related to the faster fetal growth rate. Acute appendicitis during pregnancy is more difficult to diagnose because of the enlargement of the uterus, displacement of the appendix and physiological leukocyte increase during pregnancy, etc. In addition, appendicitis during pregnancy is prone to perforation and peritonitis, which are more dangerous to both the pregnant woman and the fetus. Therefore, early diagnosis and timely management have an important impact on the prognosis. 1. Acute appendicitis during pregnancy has the following unique pathological characteristics: 1. Inflammation can easily spread after a pregnant woman has appendicitis, and the toxins produced by bacteria can affect the fetus through the blood, causing fetal hypoxia and, in severe cases, fetal death. The inflamed appendix can also directly stimulate the uterus and cause uterine contractions, resulting in preterm labor or miscarriage. During pregnancy, the pelvic organs of pregnant women are congested and the inflammation of appendix develops rapidly, so the rate of appendiceal perforation and necrosis is higher. As the number of months of pregnancy increases, the enlarged uterus can compress the cecum, appendix and ascending colon, making its blood flow impaired, peristalsis weakened, and feces can easily accumulate, so once the appendix is obstructed, it is not easy to relieve itself. 4, late pregnancy due to the enlarged uterus to the side of the large omentum, blocking the movement of the large omentum, so that it can not go to wrap the inflamed appendix, so the tail perforation after the inflammation is not easy to limit, and often into a serious diffuse peritonitis. 5, pregnant women after childbirth or premature birth, due to uterine contractions, can make the original has been limited by the inflammation and rapid spread. The treatment of acute appendicitis during pregnancy: 1, early pregnancy (1-3 months): regardless of the severity of its clinical manifestations, should be surgical treatment. 2, mid-pregnancy (4-6 months): There are different opinions on whether to actively use surgery for acute appendicitis in women with mid-pregnancy, but most believe that the appendix should be surgically removed. In addition, the safety factor of surgical treatment at this time is greater than that of early pregnancy, and it is generally believed that this is the best time for surgical removal of the appendix. 3.Late pregnancy: At this stage, the diagnosis of acute appendicitis is difficult and easily delayed, resulting in the spread of infection, which should be treated by surgery as early as possible. At the same time, even if premature delivery is caused by surgical stimulation, the majority of babies can survive and the surgery has little effect on the pregnant woman. The survival of the fetus during pregnancy with acute appendicitis does not depend on the appendectomy, but on the delay in diagnosis or delay in surgical resection. Early in pregnancy, appendicitis is easier to diagnose and the prognosis is good. The more advanced the pregnancy, the more difficult the diagnosis and the greater the chance of misdiagnosis. Delayed treatment leads to appendiceal perforation and even diffuse peritonitis, resulting in higher maternal mortality. Pregnancy is not a contraindication to appendiceal surgery, and surgery may not necessarily cause preterm delivery. To prevent the spread of inflammation, surgery should be performed as soon as possible, and a caesarean section is indicated for pregnant women with highly suspicious acute appendicitis. The aim is to avoid rapid progression of the disease, which can have serious consequences for both mother and child if it is complicated by appendiceal perforation and diffuse peritonitis.