This is the 2015 committee opinion, equivalent to a guideline, of the American Society for Reproductive Medicine (ASRM) Clinical Committee. Diagnostic evaluation for infertility is necessary for women who have had regular, uncontraceptive intercourse for 12 months or more without a successful pregnancy. Approximately 85% of couples will have a pregnancy within 12 months without medical assistance, while 15% of couples will need to be evaluated. Since female fertility declines sharply after the age of 40 years, V women over 35 years of age who have not conceived may be evaluated as early as possible if they have been trying to conceive for 6 months without conception. Early evaluation may also be considered if the following conditions (but not limited to the following) are present: History of scanty menstruation or amenorrhea Known or suspected uterine/tubal/peritoneal pathology, or heterozygosity in III-IV Known or suspected male infertility The full text is summarized as follows: Comprehensive medical, reproductive, and family histories, as well as a thorough physical examination, can identify anatomic and physiologic causes of infertility. Infertility can involve either the male or female partner, or both. Fertility declines in women after they reach the age of 40. The state of ovulation, the structure and patency of the female reproductive tract and the sperm parameters of the male affect fertility. Tests of ovarian reserve function do not constitute a diagnosis of decreased ovarian reserve function; they can be used to predict the ovarian response to exogenous gonadotropin stimulation. Hysterosalpingography is the standard protocol for checking ovarian patency. Laparoscopy is used to diagnose infertility due to peritoneal factors or tubal incompetence. Post-coital testing and endometrial biopsy do not predict reproductive potential. Full text conclusions are as follows: Diagnostic evaluation of infertility ing love includes a comprehensive history and physical examination. Diagnostic evaluation of an infertile woman should be performed in conjunction with the evaluation of the male partner. Women under 35 years of age who are not pregnant after 1 year of uncontracepted sex should seek infertility evaluation. Women over 35 years of age who have not had a pregnancy after 6 months of uncontracepted sex should seek an evaluation for infertility. Women with a clear history suggestive of scanty menstruation, amenorrhea, late-onset endometriosis (stage III-IV), or any other factor limiting fertility should seek infertility evaluation. Diagnostic evaluation for infertility should include the following tests: ovulatory function, structure and patency of the female reproductive tract, and semen analysis. Ovarian reserve function should not be routinely performed, but may be performed in elective women undergoing ovarian stimulation with exogenous gonadotropins. Laparoscopy should not be routinely performed to evaluate infertile women, but may be considered if there is a strong suspicion of advanced endometriosis, oviductal occlusive disease, or peritoneal factors of infertility. Postcoital examination and endometrial biopsy should not be part of the routine diagnostic evaluation of infertile women.