Typical anti-NMDA receptor encephalitis goes through 5 phases8 of symptoms during the course of the disease: however, not all patients have such a typical presentation, and some patients may present with only one of these symptoms or do not follow a strict progression through the 5 phases. For example, adolescents younger than 18 years of age tend to start with epilepsy and movement disorders, rather than with psychiatric symptoms as their first presentation. The following is a specific description of these 5 stages8: 1. 5 stages refers to the division of the entire course of the patient into 5 stages, which are: 1. Prodromal stage (flu-like symptoms such as headache, malaise, fever, etc.) 2. Mental disorder phase: Patients in this phase show severe mental disorders, such as bipolar disorder or schizophrenia, and are mostly seen in psychiatry. 3, non-responsive hypoventilation: Patients in this stage have reduced responsiveness to the outside world and exhibit central hypoventilation, requiring tracheal intubation. 4.Motor impairment and autonomic dysfunction phase: Patients in this phase exhibit significant motor impairment (involuntary movements) and a variety of autonomic dysfunctions. 5, recovery period or death. Second, 8 symptoms are more typical clinical symptoms of patients distilled from the above 5 stages: 1, seizures: can occur in all stages of the disease process, mostly in the early stages, manifesting as a variety of epilepsy, such as focal epilepsy, generalized epilepsy, psychomotor epilepsy, etc. 2. Mental cognitive impairment: It is mostly the first symptom, and can manifest as anxiety, irritability, bizarre behavior, delusions, paranoia, hallucinations, etc., and is often first seen by psychiatrists for this reason. 3.Memory impairment: Decline or loss of near memory. 4. Disorders of consciousness: Patients show no response to painful stimuli or refuse to open their eyes, etc. 5. Language impairment: Patients may mumble, mimic speech, or completely lose the ability to speak. 6.Motor disorders: Patients show obvious characteristic involuntary movements of the mouth, face and tongue, such as mandatory opening and closing of the mouth, abnormal facial movements, etc. In addition, there may be tardive movements of the hands and feet, choreography-like movements and limb stiffness, decreased motor function, etc. 7, autonomic dysfunction: various manifestations, including cardiac arrhythmia, blood pressure fluctuations, profuse sweating or urinary and stool dysfunction. 8, central hypoventilation: mostly due to severe autonomic dysfunction, patients often need mechanical ventilation to assist breathing. In addition, some patients also exhibit symptoms such as loss of vision/hearing and severe sleep disturbances, such as insomnia.