1. Regardless of the morphology, the presence of calcified foci in the lesion may be associated with an increased risk of thyroid cancer. It is now generally accepted that calcified foci of any form are indicative of a poor prognosis. However, microcalcifications are very common in thyroid cancer, occurring in 26-70% of patients with diagnosed thyroid cancer. However, these microcalcifications can be easily confused with colloid granules of the thyroid gland or with glandular fibrosis, which is common in chronic thyroiditis. Instead, it should be noted that microcalcifications foci are small, strongly echogenic spots (up to 1 mm) with no acoustic shadow. Unlike fibrosis, they are separate structures. Foci of microcalcifications do not form interconnected irregular strips. On ultrasound, the dense colloidal particles vibrate in response to ultrasound, resulting in a “comet tail sign”, while the microcalcifications remain stationary. 2. The shape of the nodule/focal lesion on ultrasound, i.e. “upright egg shape” or “aspect ratio >1” in cross-section or longitudinal section, is more likely to be associated with malignancy. This feature is estimated to be present in approximately 90% of cases due to the off-center growth of the malignant lesion across the normal tissue plane.