The classic staging method of diabetic nephropathy is divided into five stages, stage 1 is hyperperfusion hyperfiltration stage, stage 2 is intermittent microalbuminuria stage, stage 3 is microproteinuria stage (24-hour urinary albumin excretion between 30-300mg), stage 4 is clinical proteinuria stage, and stage 5 is renal failure stage, which is based on the observation of the natural course of type 1 diabetes, but not all type 1 diabetic patients are This is based on the observation of the natural course of type 1 diabetes, but not all patients with type 1 diabetes are in such a process, more than half of type 1 diabetes will never progress to diabetic nephropathy, so the so-called stage 1 and 2 diabetic nephropathy is not really diabetic nephropathy, but a state of renal hyperperfusion hyperfiltration due to high blood glucose, which will disappear with good blood glucose control. whether these 5 stages also exist in type 2 diabetes is not clear, because type 2 The onset of diabetes is insidious, and the existence of the above so-called stage 1 and stage 2 diabetic nephropathy states cannot be confirmed, so type 2 diabetic nephropathy can be divided into early diabetic nephropathy (stage of persistent microproteinuria), clinical diabetic nephropathy (stage of persistent urine routine examination showing proteinuria) and advanced diabetic nephropathy (stage of renal failure), and end-stage nephropathy (stage requiring renal replacement therapy such as dialysis) .