The kidney, commonly known as the “waist”, is one of the most important organs of the human body. In adults, the kidneys are close to the size of my fist and are located on each side of the spine. The kidneys have many important functions, which can be summarized in the following three aspects: 1) forming urine and excreting metabolic waste; 2) regulating the balance of water, electrolytes and acidity, and keeping the cells of internal organs living in a suitable environment; 3) the kidneys are also an important endocrine organ, capable of secreting many important hormones, such as renin, which can regulate human blood pressure, prostaglandins, erythropoietin, which promotes the production of hemoglobin, and 1-hydroxyprogesterone. The kidney is also an important endocrine organ that secretes many important hormones, such as renin, which regulates blood pressure, prostaglandins, erythropoietin, which promotes hemoglobin production, and 1-hydroxylase, which promotes the conversion of vitamin D from inactive to active and regulates calcium and phosphorus metabolism. Diabetic nephropathy is a common chronic complication of diabetes and one of the main causes of death and disability in diabetic patients. Diabetic patients are 17 times more likely to have renal failure than non-diabetic patients. The prevalence of diabetic nephropathy is higher in the Asia-Pacific region, and statistics show that the prevalence of diabetic nephropathy in Chinese patients with type 2 diabetes was 34,7% in 2001. The prevalence of diabetic nephropathy is related to the duration of the disease, with 5% of patients developing the disease within 10 to 20 years; the prevalence of >20 years is 40 to 50%. Diabetic nephropathy involves small blood vessels and glomeruli in the kidneys, resulting in albuminuria. When diabetic nephropathy occurs, due to factors such as increased blood glucose concentration, the glomerular filtration pressure increases, gradually leaking protein, if the disease is not controlled, in the long run, there will be a large amount of protein urine, to this stage, the kidney lesion has been irreversible stage, if further development, generally about 8 ~ 12 years into the renal failure stage, this stage is usually called uremia, to this stage is At this stage, dialysis and kidney replacement are needed. Early diabetic nephropathy has no obvious symptoms and is not easy to detect. But when clinical proteinuria appears, the kidney function continues to decrease, and finally it will develop into uremic syndrome, which is life-threatening. Patients not only have to suffer great physical pain, but also carry a heavy economic burden, peritoneal dialysis or hemodialysis, which costs more than 40,000 yuan a year for a patient, plus the mortality rate are high, making your life and your loved ones shrouded in the shadow of the disease. Early detection of diabetic nephropathy will likely reverse or delay the disease, so early detection of diabetic nephropathy is very important.