Acne, commonly known as acne, pimples, acne, and acne vulgaris, is known in ancient Chinese medicine as facial sores and wine spurs. Acne is a chronic inflammatory skin disease of the sebaceous gland units of hair follicles. It mainly occurs in adolescents and has a great psychological and social impact on adolescents, but can often be naturally reduced or cured after puberty. The clinical manifestations are characterized by polymorphic lesions such as acne, papules, pustules, and nodules that occur on the face. Symptoms: 1. Inflammation: Inflammation, commonly known as inflammation, refers to the physiological response stimulated by trauma, bleeding, or pathogenic infection of biological tissues. This includes symptoms such as redness, swelling, fever, and pain. 2. Blackheads: Blackheads are commonly found in adolescents during puberty, on the face, forehead and back, and are characterized by dark spots in significantly enlarged pores, shaped like small worms after extrusion, with blackened tips. 3, pustules: pustules are herpes containing pus, and pustules are also one of the most common conditions in cosmetic dermatology. Pustules are caused by the accumulation of a large number of pus cells, and this condition is easy to form scars after healing, and its main is depressed scars. Etiology: 1, immune factors: In recent years, it is believed that the disease is related to immunity, its patients in the humoral immunity, serum IgG level increased, and with the aggravation of the disease, acne rods in the patient’s body to produce antibodies, circulating antibodies reached the local involved in the pathogenic process of early inflammation. 2, trace elements: Regarding the relationship between trace elements and acne, it has recently been demonstrated that low zinc in acne patients may affect the utilization of vitamin A, prompting the keratinization of hair follicle sebaceous glands, low copper will weaken the body’s resistance to bacterial infection, etc. In short, acne patients with low trace elements zinc, copper, iron, elevated manganese can make the body fat metabolism, sex hormone secretion is somewhat affected, coupled with low skin resistance, may be associated with Acne may have a certain relationship with the development of acne. In addition to the above factors, eating more animal fats and sugary foods, gastrointestinal disorders such as indigestion or constipation, mental stress, hot and humid climate and other factors can have a negative impact on acne patients, and the exposure to mineral oils or the internal use of iodine, bromide and certain other drugs can also aggravate acne. The pathogenesis of acne is not well understood. Endocrine factors, the role of sebum, and microorganisms in the hair follicle are the main factors in the development of acne, and acne is closely related to sexual endocrinology.