I. Introduction of cell therapy Cell therapy is the abbreviation of autoimmune cell transfusion therapy.
What is autologous immune cell transfusion therapy? It means that the patient’s own cells with antiviral and anti-tumor activities are activated and expanded in vitro to selectively produce highly efficient and low-toxic antiviral and anti-tumor immune cells, and then these cells are returned to the patient’s body to achieve the purpose of virus removal and tumor cell killing.
Which immune cells from the body can take this responsibility? We know that a large number of well-defined immune cells in the human body play an important role in maintaining the body’s environment. Lymphocytes are the elite force of immune cells, while antigen-presenting cells are the radar force of immune cells. Once antigen-presenting cells detect danger signals in the body, they will transmit them to lymphocytes so that they can react quickly and go to the danger zone to eliminate the danger. In patients with tumors and chronic viral hepatitis, the number and vitality of immune cells are insufficient to detect tumor cells and viral invasion signals in time, and malignant tumor cells and invading viruses cannot be removed in time, leading to further deterioration of the disease. Cell therapy becomes the key to activate autoimmunity at this time. That is, cell therapy takes out the suppressed immune cells, mainly lymphocytes and antigen-presenting cells, from the patient’s body, and through the process of replication and activation in vitro, their quantity and activity are greatly improved, and then they are returned to the patient’s body, so as to exert anti-virus and anti-tumor effects.
The advantages and status of cell therapy can intervene early to kill tumor cells; remove residual lesions in the body and prevent tumor recurrence and metastasis. Together with chemotherapy, radiotherapy and surgery, it constitutes a comprehensive treatment for tumors.
The advantage of cell therapy is that it has no toxic side effects, can enhance the immune function of the body and improve the quality of life. It also takes a very short time to carry out the treatment.
The side effects include: chills, fever, fatigue, weakness, joint and muscle pains. They usually disappear within 24 hours.
Fourth, cell transfusion therapy includes: CIK therapy, DC-CIK therapy, and TVPLN therapy.
CIK therapy about 15 days; DC-CIK therapy about 22 days V. Indications for cell therapy Indications include a variety of solid tumors, hematologic tumors and viral hepatitis.