Chronic granulocytic leukemia treatment

There are many ways to treat chronic granulocytic leukemia.

Drug therapy: hydroxyurea, interferon, griseofulvin, dasatinib.

Hematopoietic stem cell transplantation: universal, high long-term survival rate.

Stem cells come from a variety of sources: related allogeneic, related hemizygous, unrelated allogeneic, and sibling allogeneic. Patients without siblings do not need to be discouraged, as the bone marrow bank provides a pool of about 700,000-800,000, and most people can find allogeneic donors at a slightly higher cost than kinship allogeneic.

Patients with chronic granulocytes should have the confidence to prepare for hematopoietic stem cell transplantation while on drug maintenance therapy, especially in younger patients.