The typical clinical symptoms of novel coronavirus infection include fever, malaise, dry cough, and progressive dyspnea, with some patients having mild symptoms or even no significant fever. In a small number of critically ill patients, the disease progresses rapidly and acute respiratory distress syndrome, septic shock, uncorrectable metabolic acidosis, and coagulation dysfunction soon appear, and these complications usually occur in the elderly and in those with underlying diseases. In addition to the above typical symptoms, some patients may have atypical onset of symptoms, including mild poor appetite, fatigue, lack of energy, loss of appetite, nausea, vomiting, diarrhea, headache, panic, chest tightness, conjunctivitis, and mild limb and lower back pain. It should be noted that none of these typical or atypical symptoms are specific, and neither of them can be used as a basis for the diagnosis of novel coronavirus infection, and the final diagnosis must rely on pathogenic test results.