Positive results of hepatitis B 4 and 5 tests indicate that the patient has been infected with hepatitis B virus in the past or is now in the recovery period of acute hepatitis B. It is recommended that the patient should have regular checkups on the indicators of hepatitis B two-to-half and receive treatment under the guidance of the doctor. Hepatitis B is an infectious disease caused by hepatitis B virus infection, manifesting symptoms such as pain in the liver area and fatigue, which are clinically diagnosed through the detection of hepatitis B surface antigen and other indicators. Hepatitis B surface antibody can be produced through hepatitis B vaccination to protect the human body from hepatitis B virus infection. Hepatitis B 4 and 5 tests are Hepatitis B E antibody and Hepatitis B core antibody, which are usually positive in patients who have been infected with Hepatitis B or in patients recovering from acute Hepatitis B. It is necessary to diagnose the disease with the patient’s medical history and symptoms, and carry out targeted treatment.