Patients with craniocerebral injury, especially those with severe craniocerebral injury, cannot eat, nutrient intake is insufficient, brain cells have insufficient oxygen supply and apoptosis is intensified, while factors such as insufficient cerebral ischemia and perfusion, enhanced macrophage function and increased free radicals make brain cells ischemic and hypoxic, further leading to brain failure. Therefore, proper nutritional supplementation is necessary. 1, water and sodium problems In the past, it was believed that excessive restriction of fluid intake after craniocerebral injury, and active dehydration to reduce brain pressure, but now the understanding is that excessive restriction of fluid and sodium amount section leads to hypotension and cerebral perfusion deficiency, cerebral ischemia and hypoxia to increase the morbidity and mortality rate. 2, after craniocerebral injury can be a large number of glucose infusion After craniocerebral injury, the body is in a high catabolic, high power state, and early stress hyperglycemia and respiratory depression, can not effectively use exogenous glucose as an energy source, excessive supplementation of glucose will aggravate the original stress hyperglycemia, which is not conducive to recovery from the disease. 3, craniocerebral injury after the appropriate nutritional support pathway in the face of craniocerebral injury patients, choose a suitable way of nutritional support across the important, some people think that the choice of craniocerebral injury after parenteral nutrition is safe and safe, even if the cost is expensive, but more concerns about the application of enteral nutrition, in fact, in the 2 days after the injury, the gastrointestinal volume of less than 700ml, the use or part of the use of enteral nutritional support has its Special benefits, because this can preserve the integrity of the intestinal mucosal barrier, reduce intestinal bacterial displacement, and the overview of complications such as enteric-derived infections, and it is better to choose the preparation of dietary fiber when applying enteral nutrition preparations, because dietary fiber is the energy source of the colon and helps to protect the integrity of the colon.