Childhood autism generally has a poor prognosis. In recent years, with the improvement of diagnostic ability, early intervention, and quality of rehabilitation training, the prognosis of childhood autism is gradually improving. Some children with childhood autism can reach a normal level of cognition, social adaptation and social skills. The prognosis of childhood autism is influenced by several factors, including: 1. The timing of diagnosis and intervention. Early diagnosis and long-term systematic intervention for children during the period of greatest developmental plasticity (generally before age 6) can maximize the prognosis of the child. For children with mild, normal or near-normal intelligence, early diagnosis and early intervention are especially important. 2. Early verbal communication skills. Early verbal communication ability is closely related to the prognosis of childhood autism, and the prognosis is generally better for those who have good verbal function at an early age (before 5 years old) or before the diagnosis of childhood autism is confirmed. 3. Severity of the disease and intelligence level. The prognosis of children with autism is greatly influenced by the severity of the disease and the level of intelligence. The more serious the disease, the lower the intelligence and the worse the prognosis; on the contrary, the less serious the disease, the higher the intelligence and the better the prognosis. 4. The presence or absence of concomitant diseases. The prognosis of children with autism is also related to the presence of concomitant diseases. If the child has fragile X chromosome syndrome, tuberous sclerosis, mental retardation or epilepsy, the prognosis is poor. A full understanding of the factors affecting the prognosis of the child and active treatment measures are important to improve the child’s condition and promote his or her development.