7, infection and radiation injury 1, limb and body surface anaerobic bacterial infection: due to trauma or wound contamination surgery caused by anaerobic bacteria caused by tissue infection, the condition is heavy, mostly accompanied by systemic toxic symptoms and multi-organ failure. (1) gas gangrene: mostly seen in the lower extremities, in deeper wounds and resistance to low susceptibility, surgical debridement and drainage, antibiotic-based treatment at the same time, hyperbaric oxygen therapy the sooner the better, to reduce the amputation plane, mortality can be reduced from 50-70%; to 10%; or so. (2) Tetanus: It is the most common anaerobic bacterial infectious disease with high mortality rate. Hyperbaric oxygen therapy is an adjuvant treatment, and the literature reports that the cure rate is 80%; above. (3) Intractable skin ulcers: the limited defect of skin tissue caused by infection, circulatory disorder, tumor and trauma, etc., which cannot be cured for a long time to form intractable ulcers, mostly located in the parts with relatively poor blood circulation, with heavy local soft tissue damage and contamination, combined with hyperbaric oxygen therapy on the basis of treatment of the original disease, the efficacy can be increased by 20%;. 2, radiation injury (1) radiation disease: radioactive osteonecrosis, radioactive soft tissue injury is the most common. Among them, radiation osteonecrosis of the jaw bone is more common, the efficiency of conventional anti-infection and surgical treatment is only 50.0%;, the efficiency of hyperbaric oxygen-assisted treatment can be increased to 100.0%;. (2) Radioactive soft tissue injury: mostly occurs within 6~18 months after the soft tissue is irradiated by local radiation, the clinical efficacy of conventional treatment is poor, and the auxiliary hyperbaric oxygen therapy is especially important, and its efficiency can reach 70%; or more.