Normal liver function but high total bile acids are mostly considered to be caused by physiological conditions, as well as pathological factors such as liver and bile duct diseases, which can be examined at the hospital to clarify the causes before treatment. Physiological factors: 1, people usually have high bile acid after meals, which will return to normal after a certain period of time and will not cause harm to human body; 2, the increase of estrogen and progesterone levels in pregnant women during pregnancy affects the permeability of liver cell membranes to bile acid, causing the blockage of bile outflow and stagnation in the liver, which leads to the increase of total bile acid but normal liver function. Pregnant women with high total bile acids are prone to intrahepatic cholestasis, which can seriously affect the growth and development of the fetus. Pregnant women are recommended to review their liver function regularly, especially to observe the change of total bile acids. Second, pathological factors: related to systemic lesions of the liver or bile ducts. 1, biliary obstruction, such as biliary stones, biliary tumors; 2, hepatic and portal venous shunts, which can also lead to elevated bile acids; 3, intestinal diseases that lead to impaired bile acid metabolism, which may also lead to elevated bile acids; 4, cholangitis, cholangitis, bile duct injury-induced biliary sludge; 5, acute and chronic viral hepatitis, cirrhosis alcoholic hepatitis, chronic hepatitis, etc. In addition, in daily life, we should pay attention to protect liver function, avoid staying up late, go to bed early and wake up early, do not overwork; diet should not eat spicy and stimulating food, can eat appropriate food to nourish the liver and protect the liver, quit smoking, quit drinking.