In general, small thyroid nodules do not disappear on their own, although some patients can disappear after reasonable treatment. The following are common clinical situations: 1. Patients with acute thyroiditis, the acute phase of the disease can appear enlarged thyroid gland, nodules appear, and even hyperthyroidism. After anti-inflammatory treatment, the enlarged thyroid gland can shrink and even the nodules can disappear when the inflammation is controlled and the thyroid function is normalized. 2. In addition, goiter caused by excessive iodine treatment can also be partially effective after proper control of iodine content. 3. Another type of disease is Hashimoto’s thyroiditis. In patients with Hashimoto’s thyroiditis, as the disease progresses and persists, the thyroid gland may become fibrotic, leading to a shrinking of the thyroid gland, but the disappearance of nodules is generally unlikely. Therefore, for thyroid nodules, it is advisable for patients to visit a regular hospital in order to clarify the cause as early as possible.