Viral diarrhea is a common cause of pediatric diarrhea, and rotavirus (HRV) infection accounts for about 40% of the pathogenic composition of pediatric diarrhea in China, ranking first among pediatric diarrhea pathogens. Due to the rapid change of the disease, if not treated in time, it can lead to critical conditions such as dehydration, electrolyte disturbance and shock. Data show that 350,000-590,000 children die from rotavirus diarrhea each year, and 82% of these deaths occur in developing countries, posing a serious health risk to children. HRV mainly attacks the mucosa of the small intestine, resulting in mucosal congestion, edema, loss of villi, swelling and hollowing of mitochondria, mild to moderate dilatation of the endoplasmic reticulum, impaired absorption due to microvilli degeneration, and osmotic diarrhea due to lactobiosidase degradation. In recent years, nonstructural protein 4 has been recognized as an enterotoxin, a protein that causes intracellular Ca ion accumulation and apoptosis, and enterotoxin also causes increased extracellular flow of C1 ions and reduces cellular absorption of Na+ and water, ultimately leading to diarrhea. The disease mainly occurs in infants and young children, and is prevalent in autumn and winter, and is self-limiting, generally lasting 3-8 d. It can be chronic and persistent, and is one of the causes of malnutrition and growth disorders in children. Modern medical treatment includes diet adjustment, virus inhibition, correction of water and electrolyte disorders, reconstruction of the intestinal environment, and avoidance of complications. However, ribavirin as an antiviral, treatment of this disease, the efficacy is not ideal, and there are also side effects such as white blood cell decline and gastrointestinal reactions. microorganisms. It contains flavonoids, coumarins, tannins, and phenolic acids, which have obvious antibacterial, anti-inflammatory, anti-allergic, and immune regulating effects. It can stop diarrhea and prevent diarrhea from harming yin; licorice can tonify the spleen and benefit the qi, slow down the pain, and harmonize all the medicines, which together can clear heat, resolve dampness and stop diarrhea. Some data showed that after treatment with Diarrhea I formula, the duration of diarrhea, vomiting and fever of the children was significantly shortened, and the score of damp-heat evidence after treatment was significantly lower than that of the control group, and the total effective rate was 96.67%, which was also better than that of the control group (78.33%). At present, there is no special treatment for HRV infection, and symptomatic treatment such as rehydration, antidiarrheal drugs and microecological preparations are generally used. Diarrhea I provides an idea for the treatment of HRV, and the treatment of HRV needs to be further studied.