There are two types of primary osteoporosis, osteoporosis in the elderly and postmenopausal osteoporosis, and osteoporotic fractures are the most serious complication of osteoporosis! Fracture healing requires the involvement of two types of cells: osteoblasts and osteoclasts. Osteoclasts absorb dead bone and osteoblasts then form new bone. Commonly used drugs for osteoporosis patients include calcium tablets, osteotriol, sodium allen phosphate and herbal bone-enhancing drugs. Among them, alen phosphate sodium (or other diphosphonates, such as risedronate sodium, zodronate sodium, etc.) are osteoclast-inhibiting drugs, which are core drugs for the treatment of osteoporosis. It is inferred from the theory that if alen phosphate sodium drugs are used in the early stage of fracture healing, fracture healing may be inhibited because of the inhibition of osteoclast function. At present, there are more studies in this area, and animal experiments show that: the application of sodium allen phosphate analogues in the early post-fracture period mainly affects bone plasticity in the late stage of fracture healing, with slower resorption of bone scabs and longer plasticity period, and there is no evidence that it can affect early fracture healing, but it is still in the research stage. Therefore, it is recommended to avoid oral administration of sodium allantoin phosphate drugs within the first 3 months after fracture surgery. The main applications for the treatment of osteoporosis are: calcium tablets (calcium supplementation), osteotriol (to promote calcium absorption), and herbal bone-enhancing drugs (mainly including: strong bone capsules, osteoporosis kang, compound deer antler bone building capsules, etc.). For patients with severe osteoporosis, their bone quality is very poor, and the bone is as thin as an eggshell, so it is very important to go down later after surgery, mainly to prevent further fall injury, even if a very strong internal fixation is used and anti-osteoporosis drugs are administered.