Rheumatoid arthritis (RA) is a systemic disease with symmetric polyarthritis as the mainl clinical manifestation. The basic pathological change is synovitis, with synovial cell proliferation, inflammatory cell infiltration, and vascular opacification formation. The vascular opacities can attack the cartilage and bone tissue of the joints, causing damage to the joint structure. If not treated properly, the disease gradually develops and worsens, eventually leading to deformity, joint ankylosis and loss of function, resulting in various degrees of disability. The prevalence of RA is 0.32%-0.36% in China, which is lower than the 1% in North America, 0.85% in Europe and 0.75% in India, similar to Indonesia and the Philippines (O.4%), and very rare in western Africa, and more than 2% in Jamaica. The exact cause of RA is still unknown and may be related to genetic and external environmental factors.