The treatment of acne includes topical medications, internal medications and physical therapy. The details are as follows: 1. Topical medications: such as retinoic acid cream or gel, peroxymethylphenidate, erythromycin, chloramphenicol or clindamycin, formulated with ethanol or propylene glycol, have good efficacy; 2. Internal medications: such as tetracyclines, macrolide antibiotics, isotretinoin, estrogens or anti-androgens. However, hormone therapy has more side effects and is not used as conventional therapy; 3, physical therapy: for patients who cannot tolerate drugs or do not want to accept drug therapy, physical therapy is the best choice, including photodynamic therapy, laser therapy and fruit acid therapy.