Principle of Interventional Therapy for Liver Cancer The normal liver has two sets of blood supply, one is portal vein, which collects blood from the gastrointestinal tract back to the liver, and after the detoxification of liver tissues, removes toxins and returns to the heart, this blood flow accounts for 75% of the blood supply to the liver; the second is hepatic artery, which provides arterial blood into the liver, playing the role of nutrition of liver tissues, accounting for 25%. In contrast, the blood supply of hepatocellular carcinoma tissue is completely different from that of normal liver tissue. Researchers have found that 95% of the blood supply of hepatocellular carcinoma tissue comes from the hepatic artery, which provides abundant nutrients to the cancerous tissues, and only a very small amount of portal blood supply is available in the periphery of the liver cancer mass. Therefore, blocking the blood supply from the hepatic artery to the tumor is to cut off the source of nutrients to the cancerous tissue and to “starve” the liver cancer to death, while applying chemotherapy drugs to kill the cancer cells. Interventional surgery can achieve this purpose by introducing a thin 2mm diameter catheter through femoral artery puncture and inserting it into the blood supply of hepatocellular carcinoma in the hepatic artery under the guidance of x-ray fluoroscopy. At present, the embolization agent is mixed with anti-cancer drugs to perform chemoembolization, so that the anti-cancer drugs in the embolization agent are released slowly and the therapeutic effect is better, further killing the cancer cells. Recently, Japanese scholars summarized the effect of interventional treatment for liver cancer in the past 30 years, and the results showed that the survival period of treatment for early-stage liver cancer is similar to that of surgical treatment, while the majority of patients with mid- to late-stage liver cancer, who are inoperable, have their symptoms relieved and their lives prolonged after receiving interventional treatment. Many experts believe that interventional treatment is preferred for middle and advanced stage liver cancer. Interventional treatment for liver cancer is feasible for the following patients: 1. primary or metastatic liver cancer that cannot be removed surgically for various reasons, or small liver cancer that the patient does not want to operate. 2.As a preparation before surgery, liver cancer can be shrunk through interventional treatment, which makes surgery easy to resect, and in addition, the spread and recurrence of tumor can be reduced after interventional treatment. 3.Patients whose hepatocellular carcinoma is not completely resected, relapsed after surgery or failed to be treated by other methods. 4.Hepatocellular carcinoma lesions do not rupture and bleed. 5.No serious damage of liver and kidney function. 6.Patients without severe jaundice and ascites. 7.Patients with good general condition and no serious bleeding disease. Although liver cancer is currently treated mainly by surgery and intervention, comprehensive treatment is more important, such as postoperative interventional chemotherapy for liver cancer, which can not only detect residual lesions, but also prevent recurrence and metastasis after surgery. Interventional treatment for liver cancer can shrink the tumor to obtain the chance of resection. With the continuous improvement of science and technology, interventional treatment for liver cancer is not only limited to embolization chemotherapy via hepatic artery. In addition, interventional treatment of liver cancer together with other treatments can play a complementary role, such as interventional treatment of liver cancer plus radiotherapy, immunotherapy and traditional Chinese medicine, etc. The efficacy of interventional treatment of liver cancer is also confirmed. In conclusion, liver cancer is a comprehensive treatment mainly based on surgery and intervention. Therefore, patients suffering from hepatocellular carcinoma should build up confidence, and those who are in a position to do so should go to the interventional radiology department of a general hospital for examination and treatment, and formulate a reasonable treatment plan to achieve the best treatment effect.