Esophagogastric fundic varices can be cured, and cure means that the fundic varices disappear or are reduced to less than one degree by modern treatment methods, and there is no longer any risk of bleeding. However, the cause is not resolved, and the cause of portal hypertension or cirrhosis still exists and is prone to recurrence. Follow-up treatment is required after relapse, and treatment can be given again to achieve a cure. Some patients with end-stage liver disease need to undergo liver transplantation to completely eliminate the cause of portal hypertension in order to achieve a cure and eventually make the esophageal varices free from the risk of recurrence again.