With the liberalization of the “comprehensive two-child” policy, many couples began to prepare for a healthy baby. The woman should be well prepared to welcome the second child After the age of 35 years old, often can not control their weight, but excessive obesity and underweight are not very conducive to the birth of a healthy baby. Therefore, if senior women are planning to have a second child, they need to pay attention to diet and exercise. To ensure a healthy body, senior women need to undergo a comprehensive physical examination before pregnancy to exclude some gynecological diseases, infectious diseases and systemic organic diseases, and to assess ovarian function and uterine conditions. In addition, folic acid supplements are needed before the first trimester to prevent fetal malformations. Men should be well prepared for their second child. About half of the infertility cases are due to male problems. In fact, as men age, their testicular function decreases and the quality of their sperm decreases, as do many semen parameters. The age-related alterations in sperm epigenetics may predispose the offspring to schizophrenia, malignancies and other diseases. Therefore, to have a second child, senior men also need to have a positive preparation process, such as: changing bad habits such as smoking, drinking, staying up late, and exercising more in advance. Men also need to undergo health checkups and fertility tests, such as semen analysis and sex hormones, to determine fertility indicators.