Since the establishment of Nanjing General Hospital of Nanjing Military Region in 2013 under the initiative of academician Li Jieshou, relying on the strong strength of general surgery, Professor Li Ning’s team is responsible for the establishment of the center; the center is based on the flora transplantation (FMT) technology, combined with probiotics (pectin Jinling No. 1), probiotics and nutritional support and other therapeutic means, creating a new situation for the treatment of intestinal flora imbalance diseases such as intractable constipation, Clostridium difficile infection and inflammatory It has created a new situation in the treatment of intestinal flora imbalance diseases such as intestinal constipation, Clostridium difficile infection and inflammatory bowel disease, and achieved good clinical results and social praise. Recently, the team’s experience in flora transplantation for constipation was published in the international journal (J Clin Gastroenterol), which is the first international report on intestinal microecology treatment for chronic constipation.