Uric acid is the end product of purine metabolism and is mainly produced by the enzymatic breakdown of nucleic acids and other purine analogues from cellular metabolism and purines from food. The saturation and concentration of uric acid in the body at 37℃ is about 420μmol/L (7mg/dl), and exceeding this concentration is called hyperuricemia. Uric acid is the end product of purine metabolism and is mainly produced by the enzymatic breakdown of nucleic acids and other purine analogues from cellular metabolism and purines in food. Therefore, a low purine diet is a dietary principle that should be strictly adhered to by patients with hyperuricemia. All foods with low purine content can be consumed, such as most vegetables, fruits, dairy products, rice and noodles, etc., which have low purine content and are suitable for daily consumption. However, high purine diet should be avoided into, such as seafood, animal offal, beans, mushrooms, thick broth, beer, white wine, yellow wine, etc. Moreover, since patients with hyperuricemia are prone to combine chronic diseases such as fatty liver and diabetes, their daily diet should be adjusted according to their weight, blood lipids and blood sugar level in addition to adhering to the principle of low purine. For example, for patients with combined diabetes, in addition to a low purine diet, the intake of staple foods such as rice and noodles should not be too high; and for patients with combined hyperlipidemia, in addition to a low purine diet, the intake of lipid foods should not be too high. At the same time, patients with hyperuricemia should drink plenty of water to dilute uric acid in the blood and increase its excretion at the same time. If the uric acid level is not reduced to normal level through dietary modification, medication should also be administered. The main drugs for lowering uric acid include: uric acid excreting drugs such as benzbromarone, drugs that inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, and new uric acid lowering drugs such as selective uric acid reabsorption inhibitors. Therefore, for patients with high uric acid, a low purine diet and plenty of water can play a role in lowering uric acid. For patients with hyperuricemia that cannot be controlled by diet, they should promptly enter drug therapy.