The normal value (ELISA) of d2 polymers, or D-dimer, is 0 to 0.256 mg/L. If it is higher than 0.256 mg/L, it is necessary to find out the cause and deal with it.
D-dimer comes from cross-linked fibrin clot dissolved by fibrinolytic enzyme, which is the degradation product of fibrin. Elevated level of D-dimer indicates the existence of hypercoagulable state and secondary hyperfibrinolysis in the body.
Elevated D-dimer is commonly seen in disseminated intravascular coagulation (DIC), acute promyelocytic leukemia, deep vein thrombosis, pulmonary thromboembolism, and malignancy. Clinical applications are mainly in the diagnosis of venous thromboembolism (VTE), deep vein thrombosis (DVT) and pulmonary embolism (PE). In addition, elevated D-dimer can be seen in the case of hemorrhage formed by a blood clot.
When D-dimer is found to be higher than 0.256 mg/L, it is recommended to seek medical attention from a medical professional to find out the cause of the elevation and take treatment according to the different causes.