Female genital mycoplasma infection, asymptomatic people do not need treatment, symptomatic people generally in the physician’s guidance to choose macrolide antibiotics (erythromycin, azithromycin) and tetracycline drugs (tetracycline, minocycline) treatment. 1. Macrolide antibiotics: commonly used drugs are azithromycin, roxithromycin, clarithromycin and so on. Common adverse reactions are gastrointestinal irritation, such as abdominal distension, loss of appetite, nausea and vomiting, etc. Contraindications are mainly prohibited for those who are allergic to the drugs. 2. Tetracycline drugs: commonly used drugs are tetracycline, minocycline, doxycycline and so on. Common adverse reactions are mainly gastrointestinal irritation (nausea, abdominal pain, diarrhea) and drug liver injury. Some also have allergic reactions such as skin erythema and windburn. It is contraindicated in people who are allergic to tetracyclines. Infants and children under 8 years of age, women of childbearing age should not be used during pregnancy. Women with Mycoplasma genitalium infections should seek medical attention, and all medications should be used under the guidance of a medical professional, and should not be abused blindly by yourself.