Liver cancer is one of the most common malignant tumors in China. Before ablative technologies such as radiofrequency, microwave and argon helium knife were applied in liver cancer treatment, surgery was the only radical means. Recently, more and more studies have shown that ablation therapy such as radiofrequency has comparable efficacy with surgery in the treatment of liver cancer, and has higher safety and shorter hospital stay. The literature reports that the complication rate of radiofrequency ablation therapy is about 5%, and the complication rate of surgical resection is about 27%. For patients with similar hepatocellular carcinoma, the 5-year survival rates after radiofrequency ablation and surgical resection are comparable. The efficacy can be further improved with a combination of interventional therapy (arterial chemoembolization) followed by radiofrequency ablation. Magnetic resonance of liver showing primary hepatocellular carcinoma (double arrow) CT-guided radiofrequency ablation after arterial chemoembolization After radiofrequency ablation, the tumor was completely necrotic on repeat MRI (T2) and enhanced MRI showed complete necrosis. Since then, no further treatment was performed, and the patient has been ablated for 5 years without recurrence or progression.