Usually hysterectomy does not affect immunity; the uterus, as the organ that nurtures the fetus, does not affect immunity much after removal. However, there may be ovarian hypoplasia, pelvic organ prolapse, constipation and urinary tract infection, and psychological stress. 1. Ovarian hypoplasia or premature aging: non-menopausal women will have symptoms of early menopause. The removal of the uterus will affect part of the ovarian function, for example, the function of secretion of estrogen and progesterone decreases, thus leading to early menopause. The removal of the uterus will affect the blood supply to the ovaries, which may lead to premature ovarian hypoplasia and early menopause. 2. Prolapse of pelvic organs: The uterus is located in the pelvic floor between the bladder and the rectum, and is the support for the internal organs, the bladder and the rectum. After total uterine excision, there is a possibility of pelvic organ prolapse may occur. 3. The urinary system is susceptible to infection: after hysterectomy, the level of estrogen in the body will also decrease, causing the mucous membrane of the urethra to atrophy, and the ability to resist disease and evil decreases, which will lead to symptoms such as frequent urination, urinary urgency, and painful urination. 4. Psychological stress: some patients, after total hysterectomy, may have psychological barriers and feel that they have lost their fertility and are no longer whole. When a woman performs hysterectomy, she should actively adjust her mindset, and when physical discomfort or psychological discomfort occurs, please consult a doctor in time to avoid delaying the condition.