Patient: Description of the condition (onset time, main symptoms, hospital visited, etc.): June 2011 to Changchun Medical University First Hospital check creatinine 220; urea nitrogen 13; uric acid 600; anemia and weakness; blood pressure does not take antihypertensive drugs about 150; polyuria 3000 ml; July 2011 to a hospital in Beijing has been eating Chinese medicine; with renal suppository; now creatinine 289; urea nitrogen 13, 45; uric acid 634, is there any way to keep creatinine from developing in your hospital? Mao Zhiguo: Polycystic kidney disease is characterized by numerous progressively enlarged cysts in both kidneys, accompanied by the destruction of the normal structure of the kidneys. Kidney function gradually decreases with the increase of kidney volume, from this level, the gradual decrease of kidney function is caused by the characteristics of the disease itself, and there is no way to keep creatinine from developing absolutely. However, in recent years, our institute has conducted a lot of clinical research on polycystic kidney disease and summarized some proven treatment methods and concepts, which, I should say, have slowed down the deterioration of kidney function and complications in patients with polycystic kidney disease to a certain extent. We suggest you to visit our nephrology clinic at your convenience to adjust your treatment plan.