Adherence to gout treatment is the key

  Gout, is an ancient and frequent disease. With the improvement of people’s living standard, the incidence is increasing. However, because gout has the characteristic of intermittent attacks, it causes many patients to pay insufficient attention to the disease. Some people even take uric acid-lowering drugs and drink a lot of wine and meat at the same time. They think that as long as the joints do not hurt, there is no attack. This is a serious misconception.  Gout not only affects the joints, causing swelling and pain, or even deformity, but high blood uric acid levels can also lead to deposition of uric acid in the kidneys, heart valves, cardiovascular and cerebrovascular, leading to renal insufficiency. Clinically, many patients appear to develop renal failure and uremia, and some patients develop cardiovascular events such as cardiac insufficiency, cerebral infarction and cerebral hemorrhage. Gout, therefore, is not only as simple as arthritis. It can affect metabolism such as blood sugar and blood lipids, as well as cause multiorgan and multi-system damage such as kidney, heart and brain lesions, diabetes, and hypertension. However, the most common one is gouty kidney damage.  Therefore, patients who are diagnosed with gouty arthritis require interventional treatment and may need long-term adherence to treatment. The treatment of gout is divided into acute phase treatment and chronic phase treatment. In the acute phase, inflammation should be controlled as soon as possible, and small doses of glucocorticoids, non-steroidal anti-inflammatory drugs and the old and classic colchicine can be used, and at present, biological agents are also used for the treatment of acute gout, and their clinical efficacy is also recognized. Chronic gout requires adherence to uric acid-lowering therapy, which is currently divided into drugs that promote excretion and those that inhibit uric acid production. They need to be applied under the guidance of physicians.  The patient’s uric acid level is currently recommended to be controlled below 300 micromol/liter, so that the chance of gout attack can be reduced to less than 10%. If uric acid levels are not controlled, the chances of a gout attack may increase to 80%, so long-term control of uric acid levels is the joint to prevent gout attacks. This also includes lifestyle, such as proper exercise, drinking more water, adjusting the structure of the diet and many other factors.  In conclusion, adherence to treatment is the key to treating gout, including adherence to pharmacological intervention under the guidance of a physician and adherence to a healthy lifestyle.