Why do I need ovulation treatment for IVF? A woman has one dominant follicle per menstrual cycle that eventually matures and ovulates, but the timing of ovulation of this follicle is difficult to pinpoint, the likelihood of retrieving an egg is low, and an egg may stall at some point during the in vitro fertilization process and thus not develop into a transferable embryo. The goal of an ovulation promotion program is to obtain a sufficient number of eggs in a single treatment cycle to ensure the formation of a transferable embryo, thereby increasing pregnancy rates and the efficiency of treatment. This has led to the development of a variety of ovulation-promoting drugs and protocols. At our center, the common ovulation promotion protocols are: 1. Long protocol: The long protocol requires a longer treatment time, about 30 days from the 20th day of menstruation of the previous cycle, and is one of the most commonly used ovulation promotion protocols. On the 20th day of menstruation, the doctor needs to perform ultrasound or blood sampling to determine whether it is the luteal phase after ovulation. When it is determined to be the luteal phase, the ovarian descending regulating drug GnRHa (split shot) will be injected first so that the growth of follicles on the ovaries will be controlled. 2. Short protocol: The short protocol requires a shorter period of time, basically similar to the menstrual cycle, without the need to start the preparation in the previous cycle, which takes about 10-15 days before and after. It starts with CnRHa on the 2nd or 3rd day of the menstrual cycle, along with gonadotropin injections, and continues until the night shot day. 3. Antagonist regimen: similar in duration to the short regimen, starting with gonadotropin on day 2 or 3 of the menstrual cycle, with concomitant antagonist (Stryker) when the follicles grow to about 14 mm or when estrogen rises significantly, until the day of the night injection. 4.Microstimulation regimen: The treatment time is shorter than the antagonist regimen. The patient’s ovarian condition and sex hormone levels are used to determine how to administer the medication, usually starting with oral clomiphene or letrozole on day 2 or 3 of the menstrual cycle, with gonadotropin injections during or 5 days later until the night shot day. 5. Natural cycle: Relying entirely on a woman’s natural biological cycle without any ovulation-promoting drugs, waiting for the natural dominant follicles to grow and mature, which may require night injections, or individualized egg retrieval timing based on sex hormone results. How does the doctor develop an appropriate treatment plan for the patient? When faced with multiple options, the doctor’s ability to choose comes from long clinical experience, as well as from academic exchanges both nationally and internationally. Each woman’s age, ovarian response to medications, and previous treatment outcomes and results are different, and we analyze this information together to find the most appropriate option to achieve the desired clinical pregnancy rate, which is the highest purpose and level of treatment – individualized treatment. Therefore, it is advisable to inform your doctor of your situation in detail, communicate with them, adjust your attitude, trust your doctor and try to cooperate with him/her before treatment. Relax and face everything in an optimistic and positive spirit, then a successful pregnancy is just around the corner.