1.According to post-operative neurosurgery care routine. 2, closely observe the changes in condition such as blood pressure, consciousness, pupils, etc., observe for 72h, and then observe according to medical advice as appropriate after stabilization, which is usually done under the supervision room. 3, skull base fracture ear and nose cavity with fluid outflow, covered with sterile gauze, do not fill with cotton. 4.Keep the airway unobstructed, prepare suction appliances, and be ready to do the cooperation and care of tracheotomy. 5.Pay attention to whether there are shaky teeth in the mouth, if there are, they should be removed. If there are dentures, they should be removed and given to family members for safekeeping. 6, agitated patients should add protective restraint and sedative drugs. Daily diet: 1, diet with high protein, high vitamin, low fat easily digestible food (such as fish, lean meat, eggs, vegetables, fruits, etc.) is appropriate. 2, pay attention to the combination of work and rest, to ensure sleep, can be appropriate outdoor activities (cranial defects should wear a good hat to go out, and have family members accompany to prevent accidents). 3.Tell the patient that the repair of skull defect is usually needed after six months after the traumatic brain injury surgery. 4.Take the medication as prescribed by the doctor, do not stop the medication without authorization, and follow up in the outpatient clinic one month after discharge. 5, strengthen functional exercise, if necessary, some adjuvant therapy, such as hyperbaric oxygen, etc. 6.Patients with traumatic epilepsy should take oral antiepileptic therapy according to the regular schedule. 7. Patients with traumatic hydrocephalus should undergo shunt surgery in a timely manner.