Uric acid is the end product of purine metabolism, mainly from the breakdown of nucleic acid and other purine compounds by cellular metabolism as well as purines in food by the action of enzymes. The saturation and concentration of uric acid in the body is about 420 μmol/L (7 mg/dl) at 37°C. Above this concentration, hyperuricemia is considered, and long-term hyperuricemia may lead to gout. Clinically, there are primary hyperuricemia and secondary hyperuricemia, so the treatment includes the following aspects: 1. General treatment: control the total calories in the diet; limit the consumption of alcohol and high purine food, and also recommend to control the intake of high fructose; promote the excretion of uric acid by drinking a lot of water; carefully use drugs that inhibit uric acid excretion, such as thiazides Avoid the triggering factors of gout and actively treat related diseases. 2.Treatment of hyperuricemia: The aim is to maintain the normal level of uric acid. Mainly include: uric acid excreting drugs such as benzbromarone, drugs to inhibit uric acid production such as allopurinol and febuxostat, alkaline drugs such as sodium bicarbonate, new uric acid lowering drugs such as selective uric acid reabsorption inhibitors, etc. 3.Treatment of acute gouty arthritis: Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. 4. Treatment of intermittent and chronic gout attacks: for patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. Treatment principles for secondary hyperuricemia: actively treat the primary disease; try to avoid or reduce the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control acute gouty arthritis attacks as soon as possible. In addition, hyperuricemia and gout are often associated with metabolic syndrome, and should be actively treated with comprehensive treatment such as hypotension, lipid lowering, weight reduction and improvement of insulin resistance. Therefore, for the treatment of hyperuricemia, specific treatment methods should be chosen according to the cause and condition of the patient, combined with lifestyle improvement and diet control, in order to achieve the best treatment effect.