Hepatitis B virus 6 of 10 requires antiviral treatment if it causes liver damage or cirrhosis; if there is no damage to liver function it can also be left off the medication for the time being. Hepatitis B virus 6 of 10 indicates that there is replication of the hepatitis B virus in the body, and whether antiviral treatment is needed mainly depends on the condition of liver function and whether there is liver fibrosis or cirrhosis. If the patient is also combined with abnormal liver function or cirrhosis, antiviral treatment is needed; at the same time, older patients with a family history of hepatitis B also need antiviral treatment. Antiviral drugs are usually used to treat patients with either or both of tenofovir or entecavir. Hepatitis B virus 6 does not cause liver function damage or cirrhosis, so these patients can be off the medication for the time being and undergo regular checkups. It is suggested that patients should consult the doctor in time and standardize the treatment under the doctor’s guidance, so as to avoid delaying the condition.