Women with gout tend to develop the disease after menopause, but in recent years there has been a trend toward younger onset. Initially, patients may have no specific discomfort and may only have persistent or fluctuating hyperuricemia. The early stage of gout is mostly asymptomatic, and patients may have no discomfort, but only persistent or fluctuating elevation of blood uric acid. Many patients do not even know that their blood uric acid is elevated unless they have a blood test. The asymptomatic phase of gout can last for years or decades and is associated with a number of factors, including gender, age, history of hyperuricemia, and blood uric acid levels. When gout starts to appear, the acute arthritis phase begins, with sudden onset of single joint redness, swelling and pain, mostly at night or in the morning during sleep, mostly in the joints of the lower extremities, the first metatarsal phalangeal joint is the most common, but can also spread to the knees, fingers, wrists, elbows and other joints. At this time, the patient often feels the pain and swelling of the joint as if it were a knife cut or insect bite. These joint symptoms may also resolve on their own within a few days or 2 weeks or with medication. If the condition is not well controlled, frequent acute gout attacks can lead to gout stones, which can cause chronic joint inflammation, resulting in persistent joint swelling, pain, and even joint deformity. Gout stones can also be deposited in the kidneys, causing gouty nephropathy, leading to symptoms such as hematuria, proteinuria, edema, anemia, hypertension, and renal colic. As mentioned above, female gout patients may have no obvious discomfort at the beginning, only persistent or fluctuating hyperuricemia, and as the disease progresses, they may have acute attack symptoms such as sudden single joint redness, swelling and heat. In frequent cases, symptoms due to gout stone deposition may also occur.