Gliomas originate from neurointerstitial cells, i.e., glial, ventricular canal, choroid plexus epithelium, and neuroparenchymal cells, i.e., neurons. Most tumors originate from different types of glia, but based on the similar histogenetic origin and biological characteristics, all kinds of tumors that occur in the neuroectoderm are generally referred to as gliomas. Due to the gradual enlargement of the tumor, an intracranial occupying lesion is formed and is often accompanied by peripheral cerebral edema, which produces increased intracranial pressure when the compensatory limit is exceeded. The examination of cerebrospinal fluid is as follows: 1. Lumbar puncture pressure is mostly increased. The operation should be cautious, do not put more cerebrospinal fluid, give mannitol drip after the operation, and pay attention to observation; 2.Ultrasonic examination: it can help to fix the side and observe whether there is hydrocephalus, and B-type ultrasonic scan can be performed through fontanelle for infants, which can show tumor images and other pathological changes; 3.Electroencephalography: the EEG changes of glioma are on the one hand the changes of brain waves confined to the tumor site, and on the other hand the general extensive These are affected by tumor size, infiltration, degree of cerebral edema and intracranial pressure increase, etc. Superficial tumors are prone to limited abnormalities, while deep tumors are less limited. 4. Radioisotope scan (Y-ray brain map): Tumors with fast growth and rich blood flow have high blood-brain barrier permeability and high isotope uptake rate, such as glioblastoma multiforme shows isotope concentration images, and there may be low density areas formed by necrosis and cysts in the middle, which need to be differentiated from metastases according to their shape and multiplicity. 5. Radiological examination: including cranial plain film, ventriculography and electron computed tomography, etc. Cranial plain film can show intracranial pressure increase, tumor calcification and pineal gland calcification displacement, etc. Ventriculography can show cerebral vascular displacement and tumor vascular condition, etc. These abnormal changes are different in different parts and types of tumors, which can help locate the tumor. It can show the location, scope, shape, brain tissue reaction and ventricular pressure displacement of the tumor, but it still needs to be combined with clinical consideration in order to make a clear diagnosis; 6, MRI: The diagnosis of brain tumor is more accurate than CT, and the image is clearer. It can find the tiny tumor that cannot be shown by CT, and positron emission tomography can get the image similar to CT, and can observe the growth and metabolism of tumor and identify benign malignant tumor.