Juvenile varicocele is a disease that affects the development of the testicles and leads to infertility in adulthood. Many parents don’t know much about it, and even feel that it doesn’t matter much whether they treat it or not and ignore it, and regret it when they become infertile in adulthood. In fact, varicocele is a vascular lesion of the spermatic cord, mostly seen on the left side, accounting for about 85% to 90%; 10% bilaterally. The right side is mostly seen in bilateral lesions, and cases occurring solely on the right side are rare. Varicocele is the first cause of male infertility, accounting for 35% of patients with primary infertility and 50%-80% of patients with secondary infertility. The subclinical type: the varicose veins cannot be found on palpation and when the patient holds his breath to increase the abdominal pressure (Valsalva test), and minor varicose veins can be found by color Doppler examination. Grade I: The varicose veins are not obvious on palpation, but can be palpated when the patient holds the breath and increases abdominal pressure (Valsalva test). Intraventricular spermatic angiogram shows up to 5 cm of intraventricular reflux of the contrast medium. 2. Grade II: The varicose veins can be palpated. 3. Degree III: The scrotum is enlarged and the varicose veins are visible on the surface of the scrotum with the naked eye. Causes: 1. The left internal spermatic vein has a long stroke and may be compressed by the sigmoid colon. 2, The left renal vein may be compressed by the aorta and superior mesenteric artery. 3.The right common iliac artery may compress the left common iliac vein, so that the reflux of the left spermatic vein is partially blocked. 4.The upright posture of the person affects the venous reflux. 5.The spermatic vein valve is absent or malfunctioning. Varicocele is associated with abnormal semen, decreased testicular volume, decreased testicular perfusion and testicular spermatogenic dysfunction, etc. The specific pathogenesis may be: 1. High temperature. Varicocele can increase testicular temperature, leading to spermatogenesis disorders and resulting in reduced testosterone synthesis by testicular interstitial cells. 2, high pressure. Elevated spermatic vein pressure leads to insufficient testicular perfusion. 3.Lack of oxygen. Poor venous blood return caused by varicocele can lead to testicular stasis and hypoxia, inducing germ cell apoptosis. 4.Adrenal metabolite reflux. In patients with varicocele, the blood returning from the adrenal glands can reflux along the spermatic veins, and the metabolites secreted by the adrenal glands and kidneys, such as steroids, catecholamines and 5-hydroxytryptamine, can affect testicular blood flow and cause adverse effects on the metabolism of the testes.