I. What is bipolar disorder? It’s a mood disorder. It alternates between very high and very low moods, which are different from the ups and downs of ordinary people. When the disease is severe, it can cause difficulties in family, work, study or socialization, and even cause suicide. II. Etiology There is no single cause. Family health history, brain chemistry play a major role in constituting the disease. Individual personality and stress may also trigger the disease. Symptoms The patient may experience extremes in mood, with highs and lows, and periods of normalcy between episodes. The patient may experience the following changes: High mood (can be only partially symptomatic): 1. good mood, increased activity; 2. high energy, thinking too much too fast; 3. talking more than usual or faster; 4. less sleep without feeling tired; 5. poor judgment, decreased self-control, like to spend money; 6. exaggerate their own ability, etc. Depressed mood (can be only partially symptomatic): 1. Feeling sad – crying for no clear reason; 2. Feeling hopeless or empty; 3. Feeling guilty or feeling worthless; 4. Loss of former pleasures; 5. Decreased energy or feeling tired; 6. Sleeping too much or not enough; 7. Eating more or less than before; 8, Even want to commit suicide. IV. Treatment Standardized treatment can produce a good response. Since relapses often occur, treatment must be continued. Drugs (emotional stabilizers, etc.) and psychotherapy (learning to control stress, etc.) should be used in combination. Sometimes it is necessary to change and adjust the treatment (type and dosage of medication.). Also, support from family, friends, psychotherapy and self-help groups is helpful.