Surgery is currently the most effective treatment for liver cancer. The survival rate of early stage liver cancer after surgical resection is over 80% in one year and over 50% in five years. However, postoperative recurrence is very common, so reducing postoperative recurrence is the key to improve the survival rate of surgery, so how to improve the survival rate of liver cancer after surgery? Early resection: early resection is undoubtedly the pivotal factor to improve tumor-free survival, because early liver cancer patients are very good in terms of physical quality and lesion condition, the earlier resection is better for liver cancer patients, and early diagnosis and early treatment are closely and intimately related to improving postoperative survival rate. Intraoperative prevention: Intraoperative preventive measures are also crucial to prolong tumor-free survival. The most basic point to note is to avoid squeezing the liver and tumor as much as possible during the whole operation. Increased intratumoral pressure is an important cause of hepatocellular carcinoma metastasis. Minimize intraoperative blood loss and hepatic portal block time. For those who cannot reach sufficient distance from the cutting edge, the liver wound should be treated accordingly, such as anhydrous alcohol injection, anhydrous alcohol or chemotherapy drug sponge embedding, microwave curing of liver cut surface, freezing, etc. Intravascular chemotherapeutic drug infusion, etc. should be used to aspirate and remove the visible cancer emboli. Intraoperative ultrasound is also helpful for radical resection. Drug infusion device (DDS) built into the portal vein or hepatic artery is also a desirable option. Postoperative comprehensive treatment: Postoperative comprehensive treatment has been studied more in the past, such as immunotherapy, DDS, chemotherapy and Chinese herbal medicine have also played a different degree of efficacy. Reoperation for recurrence of lesions: reoperation for recurrence is an important method to prolong survival with tumor, and the 5-year survival rate after resection of hepatocellular carcinoma can be more than 40%. Therefore, re-operation for recurrent hepatocellular carcinoma should be actively advocated for those who have the conditions.