Male infertility is a common male disease, according to statistics, one out of every eight couples of childbearing age suffers from fertility difficulties, and this number is on the rise. Infertility plagues many couples of childbearing age, causing emotional crises for couples and seriously affecting the stability of families and social harmony. The limitations of human understanding of their own reproductive physiology and pathology have added to the confusion about infertility, coupled with the many false and untrue propaganda of infertility in society and the wantonly exaggerated efficacy of some charlatan doctors on patients, adding to the misery of the majority of patients. Therefore, to further strengthen the basic and clinical research on infertility, and to provide correct guidance to patients who visit the clinic for infertility, has become an urgent task to be strengthened. It is generally believed that if a couple has a normal sexual life after marriage, without using any contraceptive measures, and fails to conceive normally for more than one year, it is called infertility, of which the male and female factors account for about 50% each. Failure to conceive due to male factor is called male infertility, and more than half of the couples will seek medical help. However, due to the lack of medical knowledge about infertility, there are more misconceptions about the diagnosis and treatment of infertility, so here is a preliminary introduction to help the majority of patients with infertility. A, a beautiful and harmonious sex life is an important guarantee of a good outcome for infertility patients. There are numerous causes of infertility, of which, sexual disharmony is an important cause of infertility. According to statistics, the proportion of sexual disharmony among infertility patients is much higher than that of the general population. Penile erectile dysfunction, ejaculation disorder and low libido have serious effects on normal conception. It is very important to actively correct various sexual dysfunctions and promote a harmonious and satisfying sexual life for couples to improve the efficacy of infertility treatment, especially to improve the success rate of natural conception. Second, although the detailed examination of infertility patients can find the relevant causes of infertility, but there are still nearly two-thirds of patients can not find a clear cause, clinically known as idiopathic infertility. Although there is no cause, empirical drug therapy can be used for idiopathic infertility. Empirical drug therapy can improve semen quality and even conception in about 70-80% of patients, but the efficacy is unlikely to reach 100%. Third, although some better results have been obtained with drug therapy, it is usually not possible to cure the patient. The goal of medication is to achieve a temporary improvement in semen quality to enable the wife to conceive. After stopping the medication, the quality of semen in most patients will return to its pre-treatment state. Therefore, during the medication period, both spouses should insist on having a normal sexual life. Many patients often can not adhere to the medication, or drug treatment intermittent, which will affect the effectiveness of the drug. Fourth, the types of drugs given in general infertility treatment are beneficial to fertility and do not cause significant adverse effects on fertility. Therefore, it is possible to conceive normally while taking the medication. Many patients are afraid to have intercourse during the daily treatment, and some couples even use termination of pregnancy after conception during the medication for fear of adverse effects on the fetus due to the medication, which are caused by the lack of understanding of infertility treatment. Fifth, the general generation of sperm generation is nearly three months, so the duration of drug treatment is usually 2-3 months a course of treatment. Many patients request a review of the efficacy of treatment one month or even one or two weeks after treatment, and at this time the efficacy of treatment has not been fully reflected, not only increasing the patient’s treatment time and examination costs, but also, and more importantly, causing a blow to the patient’s confidence and doubt about the efficacy of treatment. VI. Due to the limitations of modern medical understanding of infertility and the lack of specific and effective treatment, it is impossible to achieve 100% efficacy of any treatment. After formal treatment some patients still cannot achieve improvement in semen quality and achieve natural conception, at this time, they cannot just insist on medication and can use artificially assisted reproduction to achieve pregnancy. However, due to the relatively high cost of assisted reproduction, there is a certain success rate (for example, the success rate of IVF is usually only 30%-40%), any method of assisted reproduction without formal treatment is undesirable. Seven, the last thing to emphasize is that medication for infertility is only part of the overall treatment, and the patient’s own factors are also very important. During the treatment period, you should quit smoking, quit drinking, eat less spicy and stimulating food, eat a balanced diet, get up on time, get enough sleep, and exercise properly (especially for some overly obese patients) are very important. We wish every infertility patient good results! We wish every infertile couple to have a healthy, lively and lovely baby!