Pain in the chest when breathing deeply is mainly due to diseases of the chest wall and pleura. The most common cause is injury to the muscles of the chest wall, which causes pain when the muscles are involved in movement during deep breathing, and various causes of irritation to the pleura can cause pleurisy, which is also one of the most common causes. When there is bronchitis and lung infection, the inflammation and irritation can be aggravated by breathing, which can cause localized painful symptoms. It is necessary to go to the hospital for examination, usually to do blood routine, chest X-ray examination, also need to do electrocardiogram, cardiac ultrasound examination, according to the examination results, under the guidance of the doctor to develop a reasonable treatment plan, with drugs to actively treat.