High monocyte count refers to the normal value of monocytes is higher than the high value of the interval, under normal circumstances, the percentage of monocytes is 3%-10%, the absolute value of (0.1-0.6) × 10^9/L. Monocyte high causes are more, infants and children high monocyte count is a physiological phenomenon, no need to deal with. For adults, it is necessary to analyze the specific situation of the individual, if the mononuclear cells are only high, no other symptoms do not need to do special treatment, if the mononuclear cells caused by disease need to go to the hospital to do a detailed examination to clarify the cause of symptomatic treatment, the common causes are infectious diseases, blood diseases, gastrointestinal diseases, immune diseases and malignant tumors. 1, infectious diseases: bacterial and viral infections The common anti-infective drugs include aminoglycosides, macrolides, quinolones and other antibiotics, acyclovir, ribavirin and other antiviral drugs, ketoconazole, mycophenolate and other antifungal drugs, isoniazid, rifampin and other anti-tuberculosis drugs. 2. Blood diseases: monocytes are derived from hematopoietic stem cells in the bone marrow, so blood system diseases may also lead to changes in the number of monocytes, such as true erythrocytosis, monocytic leukemia, myelodysplastic syndrome, chronic granulocytic leukemia, etc. The main treatment modalities are active anti-infection therapy such as cyclosporine The main treatment modalities are active anti-infection therapy such as cyclosporine, stanozolol and other drugs, and blood transfusion therapy for patients with severe disease; 3, gastrointestinal diseases: common ulcerative colitis, restrictive colitis, etc. Patients can be treated with aminosalicylic acid preparations, immunosuppressants, antibacterial drugs, etc. Patients with severe disease can be treated with endoscopic administration, transplantation of intestinal flora via endoscopy or surgery; 4, immune diseases: common diseases such as systemic lupus erythematosus, rheumatoid arthritis, etc. Patients with mild symptoms can use non-steroidal anti-inflammatory drugs to relieve pain under the guidance of doctors, and some patients also need to apply antimalarials, glucocorticoids, immunosuppressants and other drugs at the same time, and serious patients need to use plasma replacement or immunosorbent therapy according to doctors’ recommendations along with biological agents; 5. Malignant tumors: such as gastric cancer, colon cancer, lung cancer, Patients with malignant tumors usually use surgical treatment to remove the lesion, and after surgery, they need to prevent tumor cell metastasis with radiotherapy, chemotherapy or targeted therapy according to the doctor’s recommendation. In addition, high monocyte count can also be seen in alcoholic liver disease, nodular disease, myositis, temporal arteritis, pregnancy and childbirth, drug reactions, etc. It is recommended that if patients find high monocyte count, they should go to the hospital in a timely manner to clarify the cause of the disease and then treat the symptoms. Improve the body’s immunity.