Most focal scleroderma rarely involves damage to internal organs and usually has a favorable prognosis. Scleroderma is an unexplained connective tissue disease characterized by the deposition and hardening of collagen fibers, resulting in limited or diffuse thickening and fibrosis of the skin as well as structural abnormalities of internal organs (including the gastrointestinal tract, lungs, kidneys, and heart). Focal scleroderma and systemic scleroderma are categorized according to the extent of the skin lesions and the involvement of internal organs. Focal scleroderma is a clinical subtype of scleroderma, which is an autoimmune disease characterized by limited thickening, stiffness, and fibrosis of the skin surface. The disease can occur anywhere in the body. Most focal sclerodermas rarely involve internal organs, and most have a favorable prognosis, with only localized skin atrophy and hypopigmentation remaining. Systemic scleroderma is often characterized by widespread sclerosis of the skin, which is relatively serious, and most of them have visceral and multi-system involvement, such as gastrointestinal bleeding, interstitial pneumonitis, pulmonary hypertension, cardiac arrhythmia, renal failure and other complications. It is recommended that patients with scleroderma consult a doctor in a timely manner and follow the doctor’s instructions for standardized diagnosis and treatment, so as not to delay the condition.