The survival cycle of scleroderma patients depends on the extent and scope of skin and important organ lesions, generally speaking, the prognosis is better for those with limited lesions and worse for those with diffuse lesions. The overall prognosis of patients with limited sclerosis is good, with a 10-year survival rate of nearly 80%. Patients with diffuse sclerosis have a wide range of skin sclerosis, which can be combined with damage to the lung, kidney, digestive system and other important organ systems, affecting organ function, and some patients can also develop critical illnesses such as renal crisis and pulmonary hypertension, with a poor overall prognosis. Therefore, once diagnosed, scleroderma patients should receive systematic and standardized treatment as soon as possible, pay attention to keeping warm, quit smoking, and reduce factors that cause recurrence of the disease.