1, must be in accordance with the doctor’s instructions to adhere to the reasonable use of drugs, can not just stop drugs on their own. Early treatment is the key. High-power UVA1 irradiation is effective for all types of skin sclerosis, especially limited, adhere to irradiation for 3~6 months, can be cured. Systemic must be supplemented with drug therapy, commonly used are prednisone about 20mg/day and penicillamine in gradually increasing doses, long-term administration of total peony glycosides as well as cumene tablets and ketotifen. The hormone is the key drug for the treatment of scleroderma, do not believe in one-sided “hormone side effects” and delay the opportunity to treat the disease. 2, to establish confidence to overcome the disease, do not spend all day negative pessimism, to be cheerful and optimistic temperament. Usually must control their emotions, emotions can not fluctuate too much, if necessary, available sedative tranquilizers. 3, Raynaud’s phenomenon: pay attention to cold and warm, try to avoid exposure to cold air or contact with cold water and cold objects; avoid various injuries; drink a small amount of alcohol to increase blood circulation, non-smoking while avoiding second-hand smoke to avoid nicotine stimulation vasoconstriction; oral vasodilators or vascular smooth muscle relaxants, etc., local application of 2% nitroglycerin ointment, 2 to 3 times a day, local necrotic ulcers available 0.5% neomycin solution or ointment. Avoid frequent rubbing of the extremities. 4, esophageal involvement: chew slowly when eating, eat less and more meals, avoid spicy too cold, too hot food, to fine and soft easily digestible food is appropriate. Walk a little after eating before lying down to avoid esophageal reflux. 5.Avoid drug abuse. 6.Adjust therapeutic drugs and observe any side effects of therapeutic drugs through outpatient follow-up.