Scleroderma is a connective tissue disease characterized by inflammation, degeneration, thickening and fibrosis of the skin leading to sclerosis and atrophy, which can cause multisystemic damage. Systemic sclerosis can involve internal organs such as the digestive tract, lungs, heart and kidneys, in addition to degenerative lesions of the skin, synovium, and finger (toe) arteries. What do I need to pay attention to in the initial treatment and follow-up of scleroderma? Expert doctors recommend: First, the first visit to the patient 1, it is best to visit the clinic on an empty stomach. 2, it is best to take a shower a day in advance, because you may have to do a skin biopsy, there are wounds can not get wet. 3. It may take 7 working days for the results of the laboratory tests to come out, so please arrange your time well. 4.Bring all the previous labs with you. 5.If you have had a biopsy, please bring a glass pathology slice (go to the hospital and pay a deposit to borrow it), only a paper report is useless. 6.Application for consultation requires ID card or a copy of the family register and family book. Second, the patients of follow-up 1, every 3 months to review the blood routine. 2.Re-check liver and kidney function in the local hospital, bring the report, and review it once in 3-4 months. 3. Review the immunity index once a year. 4.Re-check for problems at any time for several times. 5.I can not come due to various reasons, please ask the agent to tell the doctor about the patient’s recent situation, and bring the blood test and liver and kidney function labs to prescribe medication.