Targeted drugs are generally used to treat pleural effusions caused by tumors. Targeted drugs are clinically defined as agents and medications that are endowed with the ability to be targeted, with the main purpose being to allow the carrier or drug to target a specific lesion location and release or accumulate active ingredients, mainly for most malignant tumor diseases. If the pleural effusion is caused by malignant tumor disease, in this case it is possible to use targeted drugs to treat pleural effusion. However, if the patient has a large amount of pleural effusion and causes discomfort, it is necessary to go to the hospital immediately to take the method of puncture drainage to carry on the treatment, at this time can not rely solely on the targeted drugs to treat pleural effusion. It is recommended to go to the hospital immediately for examination and treatment under the guidance of the doctor to avoid life-threatening treatment.