The difference between multiple hepatocellular carcinoma and multiple liver cysts mainly lies in the fact that multiple hepatocellular carcinoma belongs to a malignant disease of the liver and multiple liver cysts belong to a benign disease of the liver. Multiple hepatocellular carcinoma belongs to a relatively advanced disease of the liver, which is not easily treated because there are multiple hepatocellular tissues in the liver area, which can easily form recurrence or metastasis. Multiple hepatocellular carcinoma is a benign disease because multiple hepatocellular carcinomas are relatively cystic and occupy most of the liver tissues, and surgical resection is an effective treatment. The treatment of multiple hepatic cysts is mainly through a combination of surgery, radiofrequency ablation, radiotherapy, targeted therapy, chemotherapy and immunotherapy.